DPOAE in case medicated with cisplatin.

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Cisplatin ototoxicity, increased DPOAE amplitudes, and magnesium deficiency. Distortion product otoacoustic emissions.

Outer hair cell (OHC) metabolism is blocked by cisplatin. Concurrent changes in the renal handling of magnesium occur because of the damage cisplatin causes to the renal proximal tubule cells within the thick ascending loop of Henle. Although there is no evidence of cisplatin within the OHCs, there are significant levels of intracellular calcium, the antagonist to magnesium at the cell membrane...

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The distortion product otoacoustic emission (DPOAE) fine structure is revealed, when measuring DPOAE with a very fine frequency resolution. It is characterized by consistent maxima and minima with notches of up to 20 dB depth. The fine structure is known also from absolute hearing thresholds, and has recently been demonstrated to exist in low level equal-loudness contours. The character of the ...

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Dpoae Measurements in Factory Workers with Cochlear Hearing Loss

The main aim of the study was to find a correlation between the pure-tone threshold measured by a classic audiometer and estimated from input/output function of distortion product otoacoustic emission. The measurements were performed for a group of 27 factory workers and a control group of 10 young subjects with normal hearing (YNH). The interrelations between the results of these two methods w...

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Latency of DPOAE in milliseconds and waves Summary

The latency of Distortion Product Otoacoustic Emissions is defined as the time interval between the wave onset from initial stimulation and the return to the ear canal. Aim: The aim of this research was to verify the latency of the distortion product otoacoustic emissions in normal hearing adults, analyzing the influence of the gender, ear, frequencies and measurements. Study design: clinical p...

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ژورنال

عنوان ژورنال: AUDIOLOGY JAPAN

سال: 1996

ISSN: 1883-7301,0303-8106

DOI: 10.4295/audiology.39.547